SpectraST

SpectraST performs spectral library searching of peptide MS/MS data to match experimental spectra to reference spectra for peptide and protein identification in proteomics.

Key Features:

• Library Searching: Compares experimental peptide MS/MS spectra against a curated spectral library to identify peptides and infer proteins.

Scientific Applications:

• Proteomics Research: Facilitates identification of proteins in complex biological samples using peptide MS/MS spectral matches.
• Disease Biomarker Discovery: Assists in detecting potential biomarkers for diseases such as COPD and neuropsychiatric disorders via spectral identification of peptides and proteins.
• Nutritional Studies: Analyzes protein content in dietary studies, including prenatal nutrition, through spectral matching of peptides.

Methodology:

Matches experimental peptide MS/MS spectra against entries in a curated spectral library for peptide identification.