SPLACE
SPLACE automates splitting, aligning, and concatenating gene sequences to produce concatenated supermatrix FASTA files for phylogenomic analyses.
Key Features:
- Automated Processing: Automates splitting, aligning, and concatenating gene sequences from multiple species.
- Supermatrix Generation: Generates supermatrix files by aligning and concatenating genes for downstream phylogenetic tree construction.
- Handling Missing Data: Manages missing data in gene sequences to support robust phylogenomic analyses.
- Speed and Efficiency: Produces a supermatrix FASTA file containing 83 aligned and concatenated genes from 270 plant species within minutes.
Scientific Applications:
- Phylogenomic analyses: Enables construction of concatenated gene supermatrices for phylogenetic inference across multiple taxa.
- Evolutionary biology: Facilitates comparative analyses of gene sequences to study evolutionary relationships.
- Plant genomics: Supports large-scale phylogenomic studies in plants, including datasets spanning hundreds of species.
Methodology:
Three computational steps: splitting gene sequences, aligning sequences, and concatenating aligned sequences into a supermatrix FASTA file for phylogenetic tree construction.
Topics
Details
- License:
- GPL-3.0
- Cost:
- Free of charge
- Tool Type:
- command-line tool
- Operating Systems:
- Mac, Linux, Windows
- Programming Languages:
- Python, Shell
- Added:
- 2/13/2023
- Last Updated:
- 11/24/2024
Operations
Publications
Oliveira RRM, Vasconcelos S, Oliveira G. SPLACE: A tool to automatically SPLit, Align, and ConcatenatE genes for phylogenomic inference of several organisms. Frontiers in Bioinformatics. 2022;2. doi:10.3389/fbinf.2022.1074802. PMID:36568700. PMCID:PMC9772462.
PMID: 36568700
PMCID: PMC9772462
Funding: - Instituto Tecnológico Vale: R100603.85.0X.CB01
- Conselho Nacional de Desenvolvimento Científico e Tecnológico: 444227/2018-0 307479/2016-1