SPLACE

SPLACE automates splitting, aligning, and concatenating gene sequences to produce concatenated supermatrix FASTA files for phylogenomic analyses.


Key Features:

  • Automated Processing: Automates splitting, aligning, and concatenating gene sequences from multiple species.
  • Supermatrix Generation: Generates supermatrix files by aligning and concatenating genes for downstream phylogenetic tree construction.
  • Handling Missing Data: Manages missing data in gene sequences to support robust phylogenomic analyses.
  • Speed and Efficiency: Produces a supermatrix FASTA file containing 83 aligned and concatenated genes from 270 plant species within minutes.

Scientific Applications:

  • Phylogenomic analyses: Enables construction of concatenated gene supermatrices for phylogenetic inference across multiple taxa.
  • Evolutionary biology: Facilitates comparative analyses of gene sequences to study evolutionary relationships.
  • Plant genomics: Supports large-scale phylogenomic studies in plants, including datasets spanning hundreds of species.

Methodology:

Three computational steps: splitting gene sequences, aligning sequences, and concatenating aligned sequences into a supermatrix FASTA file for phylogenetic tree construction.

Topics

Details

License:
GPL-3.0
Cost:
Free of charge
Tool Type:
command-line tool
Operating Systems:
Mac, Linux, Windows
Programming Languages:
Python, Shell
Added:
2/13/2023
Last Updated:
11/24/2024

Operations

Publications

Oliveira RRM, Vasconcelos S, Oliveira G. SPLACE: A tool to automatically SPLit, Align, and ConcatenatE genes for phylogenomic inference of several organisms. Frontiers in Bioinformatics. 2022;2. doi:10.3389/fbinf.2022.1074802. PMID:36568700. PMCID:PMC9772462.

PMID: 36568700
PMCID: PMC9772462
Funding: - Instituto Tecnológico Vale: R100603.85.0X.CB01 - Conselho Nacional de Desenvolvimento Científico e Tecnológico: 444227/2018-0 307479/2016-1