Storage-D

Storage-D enables practical and personalized DNA data storage by allowing users to convert data into DNA sequences and vice versa through selectable algorithms, error-correction, and codec pin strategies.

Key Features:

• Wukong Algorithm: The platform incorporates the newly designed Wukong algorithm, which provides over 20 trillion codec pins for data privacy use.
• Sequence Composition Control: The Wukong algorithm controls GC content to selected standards and adjusts homopolymer run length to defined levels.
• Coding Efficiency: The Wukong algorithm maintains a high coding potential of approximately 1.98 bits per nucleotide.
• Configurable Strategies: Users can select algorithms, error-correction, random-access, and codec pin strategies according to their requirements.
• Variable Sequence Length: Users can convert data into DNA sequences of any length and vice versa.

Scientific Applications:

• In Vitro DNA Storage: The platform has been used to store the Diagnosis and treatment protocol for COVID-19 patients into 200 nt oligo pools in vitro.
• In Vivo DNA Storage: The platform has been used to store data as 500 bp genes in vivo, which replicated in both normal and extreme bacteria.
• Data Privacy: The Wukong algorithm enables data privacy protection through its extensive codec pin system.

Methodology:

Storage-D connects to a commercial DNA synthesis and sequencing platform for physical DNA storage. The Wukong algorithm encodes data with controllable GC content and homopolymer run length constraints while maximizing coding potential.