stretcher
stretcher aligns two sequences globally using the Needleman-Wunsch algorithm to produce optimal nucleotide and protein sequence comparisons.
Key Features:
- Global Alignment: Performs global pairwise alignment of two sequences, comparing entire sequence lengths.
- Needleman-Wunsch Algorithm: Uses the Needleman-Wunsch dynamic programming algorithm to compute optimal alignments.
- Sequence Types: Handles both nucleotide and protein sequences for pairwise comparison.
- EMBOSS Integration: Integrated within the European Molecular Biology Open Software Suite (EMBOSS), enabling interoperability with other EMBOSS applications.
- Implementation: Implemented using EMBOSS C programming libraries for efficient performance.
Scientific Applications:
- Molecular Biology Research: Facilitates analysis and comparison of nucleotide or protein sequences to investigate genetic relationships and function.
- Functional Annotation and Evolutionary Studies: Supports identification of sequence similarities and differences to aid functional annotation and evolutionary inference.
Methodology:
Performs pairwise global alignment using the Needleman-Wunsch algorithm. Implemented using EMBOSS C programming libraries.
Topics
Collections
Details
- License:
- GPL-3.0
- Maturity:
- Mature
- Cost:
- Free of charge
- Tool Type:
- command-line tool
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- C
- Added:
- 11/8/2015
- Last Updated:
- 12/10/2018
Operations
Data Inputs & Outputs
Pairwise sequence alignment
Publications
Rice P, Longden I, Bleasby A. EMBOSS: The European Molecular Biology Open Software Suite. Trends in Genetics. 2000;16(6):276-277. doi:10.1016/s0168-9525(00)02024-2.
Bleasby AJ, Ison JC, Rice PM. EMBOSS Administrator's Guide. Unknown Journal. 2011. doi:10.1017/cbo9781139151399.
Ison JC, Rice PM, Bleasby AJ. EMBOSS Developer's Guide. Unknown Journal. 2011. doi:10.1017/cbo9781139151405.
Documentation
Terms of use
http://emboss.open-bio.org/html/dev/ch01s01.htmlCitation instructions
http://emboss.open-bio.org/html/use/pr02s04.html