stretcher

stretcher aligns two sequences globally using the Needleman-Wunsch algorithm to produce optimal nucleotide and protein sequence comparisons.


Key Features:

  • Global Alignment: Performs global pairwise alignment of two sequences, comparing entire sequence lengths.
  • Needleman-Wunsch Algorithm: Uses the Needleman-Wunsch dynamic programming algorithm to compute optimal alignments.
  • Sequence Types: Handles both nucleotide and protein sequences for pairwise comparison.
  • EMBOSS Integration: Integrated within the European Molecular Biology Open Software Suite (EMBOSS), enabling interoperability with other EMBOSS applications.
  • Implementation: Implemented using EMBOSS C programming libraries for efficient performance.

Scientific Applications:

  • Molecular Biology Research: Facilitates analysis and comparison of nucleotide or protein sequences to investigate genetic relationships and function.
  • Functional Annotation and Evolutionary Studies: Supports identification of sequence similarities and differences to aid functional annotation and evolutionary inference.

Methodology:

Performs pairwise global alignment using the Needleman-Wunsch algorithm. Implemented using EMBOSS C programming libraries.

Topics

Collections

Details

License:
GPL-3.0
Maturity:
Mature
Cost:
Free of charge
Tool Type:
command-line tool
Operating Systems:
Linux, Windows, Mac
Programming Languages:
C
Added:
11/8/2015
Last Updated:
12/10/2018

Operations

Data Inputs & Outputs

Publications

Rice P, Longden I, Bleasby A. EMBOSS: The European Molecular Biology Open Software Suite. Trends in Genetics. 2000;16(6):276-277. doi:10.1016/s0168-9525(00)02024-2.

Bleasby AJ, Ison JC, Rice PM. EMBOSS Administrator's Guide. Unknown Journal. 2011. doi:10.1017/cbo9781139151399.

Ison JC, Rice PM, Bleasby AJ. EMBOSS Developer's Guide. Unknown Journal. 2011. doi:10.1017/cbo9781139151405.

Documentation

Downloads

Links