STRprofiler

STRprofiler provides methods for efficient comparisons of short tandem repeat profiles for biomedical model authentication.

Key Features:

• STR Profile Comparison: Enables comparison of sets of STR profiles to each other or an existing database in a high-throughput manner.
• Cross-Contamination Detection: Provides methods for detecting cross-contamination in STR profile datasets.
• Database Flexibility: Can be run with custom databases or used to query against the Cellosaurus cell line database.

Scientific Applications:

• Biomedical Model Authentication: Supports authentication of biomedical models of human origin through STR profiling.
• Cell Line Verification: Facilitates verification of cell line identity by querying against the Cellosaurus cell line database.

Methodology:

STRprofiler implements computational methods for STR profile comparison and cross-contamination detection; specific algorithmic details are not explicitly stated in the sources.