SubSeqer
SubSeqer identifies and characterizes repetitive elements within low-complexity protein sequences using a graph-based visualization approach inspired by methods from protein interaction studies.
Key Features:
- Repetitive element detection: Identifies repetitive elements within low-complexity protein sequences.
- Repeat characterization: Characterizes the properties and patterns of detected repetitive elements.
- Graph-based visualization: Employs a novel graphical visualization approach inspired by protein interaction study methods to represent repeats.
- Low-complexity focus: Targets sequences with limited amino acid diversity that are typically challenging for conventional analyses.
- Complementary to pattern-matching algorithms: Addresses cases where traditional pattern-matching algorithms struggle due to absence of rigid motifs.
- Exploratory analysis support: Facilitates exploration and analysis of the roles and properties of repeats in proteins.
Scientific Applications:
- Protein structure analysis: Enables investigation of how repetitive low-complexity regions contribute to protein structure.
- Protein function annotation: Supports studies of the functional roles of repetitive elements in proteins.
- Evolutionary studies: Supports research into the evolution of proteins through analysis of repetitive low-complexity regions.
Methodology:
Graph-based visualization methods inspired by protein interaction studies are used to identify and characterize repetitive elements in low-complexity protein sequences.
Topics
Details
- Tool Type:
- web application
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- Java
- Added:
- 5/2/2017
- Last Updated:
- 11/25/2024
Operations
Publications
He D, Parkinson J. SubSeqer: a graph-based approach for the detection and identification of repetitive elements in low-complexity sequences. Bioinformatics. 2008;24(7):1016-1017. doi:10.1093/bioinformatics/btn073. PMID:18304932.
PMID: 18304932