SubSeqer

SubSeqer identifies and characterizes repetitive elements within low-complexity protein sequences using a graph-based visualization approach inspired by methods from protein interaction studies.


Key Features:

  • Repetitive element detection: Identifies repetitive elements within low-complexity protein sequences.
  • Repeat characterization: Characterizes the properties and patterns of detected repetitive elements.
  • Graph-based visualization: Employs a novel graphical visualization approach inspired by protein interaction study methods to represent repeats.
  • Low-complexity focus: Targets sequences with limited amino acid diversity that are typically challenging for conventional analyses.
  • Complementary to pattern-matching algorithms: Addresses cases where traditional pattern-matching algorithms struggle due to absence of rigid motifs.
  • Exploratory analysis support: Facilitates exploration and analysis of the roles and properties of repeats in proteins.

Scientific Applications:

  • Protein structure analysis: Enables investigation of how repetitive low-complexity regions contribute to protein structure.
  • Protein function annotation: Supports studies of the functional roles of repetitive elements in proteins.
  • Evolutionary studies: Supports research into the evolution of proteins through analysis of repetitive low-complexity regions.

Methodology:

Graph-based visualization methods inspired by protein interaction studies are used to identify and characterize repetitive elements in low-complexity protein sequences.

Topics

Details

Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Programming Languages:
Java
Added:
5/2/2017
Last Updated:
11/25/2024

Operations

Publications

He D, Parkinson J. SubSeqer: a graph-based approach for the detection and identification of repetitive elements in low-complexity sequences. Bioinformatics. 2008;24(7):1016-1017. doi:10.1093/bioinformatics/btn073. PMID:18304932.

Documentation