SVM2CRM

SVM2CRM detects cis-regulatory elements using linear support vector machine classification via LiblineaR within the Bioconductor R environment to analyze genomic sequences.


Key Features:

  • Support Vector Machine Implementation: Implements linear support vector machine classification to identify patterns associated with cis-regulatory elements.
  • Integration with LiblineaR: Employs the LiblineaR package for efficient implementations of linear SVMs.
  • Bioconductor Integration: Operates within the Bioconductor framework to interoperate with genomics analysis packages.
  • R-based Implementation: Built on the R statistical programming language for analysis and scripting.

Scientific Applications:

  • Cis-Regulatory Element Detection: Identifies promoters, enhancers, silencers, and insulators to support studies of transcriptional regulation.
  • Genomics Research: Facilitates functional genomics, comparative genomics, and evolutionary biology investigations by enabling detection of regulatory regions.

Methodology:

Implements linear support vector machine classification using the LiblineaR package in R within the Bioconductor framework to distinguish regulatory from non-regulatory genomic sequences.

Topics

Collections

Details

License:
GPL-3.0
Tool Type:
command-line tool, library
Operating Systems:
Linux, Windows, Mac
Programming Languages:
R
Added:
1/17/2017
Last Updated:
11/25/2024

Operations

Data Inputs & Outputs

Publications

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.

Documentation

Downloads