SWCRTsimulator

SWCRTsimulator facilitates sample size and statistical power estimation for interval-censored time-to-event outcomes in stepped wedge cluster randomized trials using Monte Carlo simulations.

Key Features:

• Monte Carlo Simulation: The platform employs Monte Carlo simulations to account for study design features and provide accurate statistical power estimates when closed-form solutions are not feasible.
• Heterogeneous Intervention Effects: The simulator accommodates heterogeneity in intervention effect across different clusters.
• Customizable Visualizations: SWCRTsimulator provides customizable visualizations for simulation results.

Scientific Applications:

• Pediatric HIV Disclosure Intervention Trials: The platform was illustrated using the Sankofa 2 trial, an active multi-clinic stepped wedge cluster randomized trial of a pediatric HIV disclosure intervention in Ghana.
• Public Health and Clinical Research: SWCRTsimulator supports evaluations of interventions rolled out sequentially across clusters in public health and clinical research settings.

Methodology:

Monte Carlo simulations.