syco

syco generates synonymous codon usage statistics and plots from nucleotide sequences within the EMBOSS framework to characterize codon preferences.


Key Features:

  • Synonymous Codon Usage Analysis: Calculates synonymous codon usage statistics from nucleotide sequences.
  • Plot Generation: Produces statistical plots that visualize codon usage patterns.
  • EMBOSS Integration: Implements functionality using EMBOSS C programming libraries and APIs.

Scientific Applications:

  • Gene Expression Optimization: Informs optimization of gene sequences for recombinant protein production by revealing codon preferences.
  • Evolutionary Studies: Supports analysis of evolutionary pressures on codon usage across species or populations.
  • Synthetic Biology: Enables design of genes with specified codon usage profiles for synthetic constructs.

Methodology:

Processes nucleotide sequences to calculate synonymous codon usage statistics, generates corresponding plots, and leverages EMBOSS C libraries and APIs.

Topics

Collections

Details

License:
GPL-3.0
Maturity:
Mature
Cost:
Free of charge
Tool Type:
command-line tool
Operating Systems:
Linux, Windows, Mac
Programming Languages:
C
Added:
11/8/2015
Last Updated:
12/10/2018

Operations

Data Inputs & Outputs

Coding region prediction

Publications

Rice P, Longden I, Bleasby A. EMBOSS: The European Molecular Biology Open Software Suite. Trends in Genetics. 2000;16(6):276-277. doi:10.1016/s0168-9525(00)02024-2.

Bleasby AJ, Ison JC, Rice PM. EMBOSS Administrator's Guide. Unknown Journal. 2011. doi:10.1017/cbo9781139151399.

Ison JC, Rice PM, Bleasby AJ. EMBOSS Developer's Guide. Unknown Journal. 2011. doi:10.1017/cbo9781139151405.

Documentation

Downloads

Links