syco
syco generates synonymous codon usage statistics and plots from nucleotide sequences within the EMBOSS framework to characterize codon preferences.
Key Features:
- Synonymous Codon Usage Analysis: Calculates synonymous codon usage statistics from nucleotide sequences.
- Plot Generation: Produces statistical plots that visualize codon usage patterns.
- EMBOSS Integration: Implements functionality using EMBOSS C programming libraries and APIs.
Scientific Applications:
- Gene Expression Optimization: Informs optimization of gene sequences for recombinant protein production by revealing codon preferences.
- Evolutionary Studies: Supports analysis of evolutionary pressures on codon usage across species or populations.
- Synthetic Biology: Enables design of genes with specified codon usage profiles for synthetic constructs.
Methodology:
Processes nucleotide sequences to calculate synonymous codon usage statistics, generates corresponding plots, and leverages EMBOSS C libraries and APIs.
Topics
Collections
Details
- License:
- GPL-3.0
- Maturity:
- Mature
- Cost:
- Free of charge
- Tool Type:
- command-line tool
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- C
- Added:
- 11/8/2015
- Last Updated:
- 12/10/2018
Operations
Data Inputs & Outputs
Coding region prediction
Inputs
Publications
Rice P, Longden I, Bleasby A. EMBOSS: The European Molecular Biology Open Software Suite. Trends in Genetics. 2000;16(6):276-277. doi:10.1016/s0168-9525(00)02024-2.
Bleasby AJ, Ison JC, Rice PM. EMBOSS Administrator's Guide. Unknown Journal. 2011. doi:10.1017/cbo9781139151399.
Ison JC, Rice PM, Bleasby AJ. EMBOSS Developer's Guide. Unknown Journal. 2011. doi:10.1017/cbo9781139151405.
Documentation
Terms of use
http://emboss.open-bio.org/html/dev/ch01s01.htmlCitation instructions
http://emboss.open-bio.org/html/use/pr02s04.html