SynTView

SynTView provides interactive comparative visualization and exploration of microbial genomes to analyze synteny and polymorphisms from Next-Generation Sequencing (NGS) datasets.

Key Features:

• Comparative visualization: Generic genome browser with sub-maps presenting syntenic organization and chromosome-level comparisons across microbial species.
• Polymorphism visualization: Visualization of polymorphism data, including Single Nucleotide Polymorphisms (SNPs), along genomes to analyze intra- and inter-strain variation.
• Multiple coordinated views: Dynamically linked specialized views including linear and circular multi-genome representations, dot plots, phylogenetic profiles, and SNP density maps.
• Data integration: Architecture not tied to a specific database, allowing import of user datasets and use of external web services.

Scientific Applications:

• Comparative genomics: Presentation and analysis of syntenic organizations and chromosome rearrangements across species.
• Evolutionary biology: Analysis of phylogenetic profiles and patterns of genomic variation for evolutionary inference.
• Microbial genetics: Investigation of SNPs and genomic organization within and between microbial strains.
• Genome sequencing projects: Interpretation and visualization of large datasets produced by Next-Generation Sequencing (NGS) efforts.

Methodology:

Integration of multiple dynamically linked genomic views to explore relationships between genomic features, supported by a flexible architecture that accommodates user datasets and external data sources.