Tablet

Tablet visualizes next-generation sequence assemblies and alignments to enable detailed inspection and interpretation of genomic data.

Key Features:

• Input format support: Accepts various assembly and alignment input formats for visualization.
• Visualization modes: Renders packed and stacked views to display read alignments at different densities.
• Contig overview and navigation: Provides whole-contig overviews, immediate navigation to regions of interest, and detailed data summaries.
• Multi-core processing: Is multi-core aware and leverages parallel processing to handle large datasets.
• Memory-efficient handling: Manages assemblies containing millions of reads, including operation on 32-bit desktop machines.

Scientific Applications:

• Sequence alignment interpretation: Facilitates visual interpretation of sequence alignments and identification of alignment features.
• Assembly exploration: Enables examination of whole contigs and read-level details for assembly inspection.
• Large-scale genomics analysis: Supports analysis workflows that require visualization of assemblies comprising millions of reads.

Methodology:

Processes assembly and alignment input formats to render packed and stacked views, provide whole-contig overviews and region navigation, and employs multi-core processing and memory-efficient handling of large assemblies.