TAMPA

TAMPA visualizes and compares taxonomic profiles produced by taxonomic profilers to support interpretation of taxa and their relative abundance in whole-genome sequencing metagenomic samples.

Key Features:

• Comprehensive visualization: Generates detailed visualizations of taxonomic profiles from diverse taxonomic profilers.
• Comparison beyond single metrics: Compares profiler outputs beyond single-value metrics such as the F1 score to reveal biological differences.
• Highlighting taxonomic distinctions: Identifies and emphasizes taxonomic distinctions and relative abundance shifts across samples.
• Profiler comparison for method selection: Facilitates comparison of profiling methods to aid selection of suitable taxonomic profilers for a dataset.
• Facilitating interpretation: Provides interpretive views of profiler outputs to support downstream biological analysis.

Scientific Applications:

• Benchmarking taxonomic profilers: Enables evaluation and comparison of taxonomic profilers using visual analyses beyond single-value metrics.
• Method selection for metagenomics: Supports choosing appropriate taxonomic profiling methods for whole-genome sequencing metagenomic samples.
• Detection of biological differences: Reveals taxonomic differences and abundance changes between samples to inform biological conclusions.
• Hypothesis generation: Highlights taxonomic distinctions across samples to generate novel biological hypotheses.

Methodology:

Performs comparative visualization and analysis of taxonomic profiles produced by taxonomic profilers, emphasizing comparisons beyond single-value metrics such as the F1 score.