targetHub

targetHub integrates miRNA-gene interaction data into a CouchDB-backed resource for incorporation into high-throughput genomic analyses.


Key Features:

  • Comprehensive Database: Provides an extensive repository of miRNA-gene interaction data.
  • RESTful Web Access: Exposes RESTful web services for programmatic querying and retrieval of interaction records.
  • Versatile Identifier Support: Accepts a variety of gene and miRNA identifiers to enable compatibility across datasets.

Scientific Applications:

  • Integration with High-Throughput Analyses: Enables incorporation of miRNA-gene interaction data into analyses of microarrays and next-generation sequencing datasets.
  • Downstream Target Analysis: Supports downstream analysis of miRNA targets to aid interpretation of miRNA-mediated gene regulation in genomic studies.

Methodology:

Implemented as a CouchDB NoSQL database and exposes RESTful web services for programmatic access.

Topics

Details

Tool Type:
api
Operating Systems:
Linux, Windows, Mac
Programming Languages:
R, Perl
Added:
8/3/2015
Last Updated:
11/25/2024

Operations

Publications

Manyam G, Ivan C, Calin GA, Coombes KR. targetHub: a programmable interface for miRNA–gene interactions. Bioinformatics. 2013;29(20):2657-2658. doi:10.1093/bioinformatics/btt439. PMID:24013925. PMCID:PMC3789542.

Documentation

Links