TCM2COVID

TCM2COVID curates a comprehensive database of traditional Chinese medicine formulas, herbs, and natural products annotated with clinical evidence and therapeutic mechanisms relevant to prevention, treatment, and recovery from coronavirus infectious disease 2019 (COVID-19).

Key Features:

• Extensive database: Over 280 traditional Chinese medicine formulas and more than 300 herbs are documented with associated clinical evidence and therapeutic mechanism information.
• Natural products repository: Records over 80 natural products (NPs) with annotations of their potential therapeutic mechanisms against COVID-19.
• Formula similarity analysis: Provides formula similarity analysis to identify similarities between TCM formulas for comparative studies of components and mechanisms.
• Clinical evidence annotation: Documents clinical evidence linked to TCM formulas and natural products to support research and validation efforts.

Scientific Applications:

• Mechanism elucidation: Enables analysis of therapeutic mechanisms of TCM formulas and natural products against COVID-19.
• Development of new therapies: Supports identification of effective ingredients and combinations from TCM to guide anti-COVID therapy development.
• Clinical research support: Provides documented clinical evidence to inform study design and validation of TCM treatments in diverse patient populations.

Methodology:

Data were compiled through meticulous manual curation and a structured approach to documenting therapeutic mechanisms and clinical evidence.