TESLA

TESLA estimates time-varying networks from time-series nodal attribute data using temporally smoothed ℓ1-regularized logistic regression to recover sparse dynamic structures.


Key Features:

  • Dynamic Network Estimation: Captures temporal evolution of network topology including topological rewiring and semantic changes across time.
  • Temporally Smoothed ℓ1-Regularized Logistic Regression: Implements logistic regression with temporal smoothing and ℓ1 regularization to model time-varying interactions.
  • Lasso-Style Sparse Structure Recovery: Uses ℓ1-regularization to produce sparse and interpretable network structures suitable for high-dimensional data.
  • Convex Optimization Framework: Formulates the estimation as a standard convex optimization problem solvable with generic convex solvers for scalability to large networks.

Scientific Applications:

  • Biological Systems: Reverse engineering of gene regulatory networks in Drosophila melanogaster, applied to datasets of over 4,000 genes across the organism's life cycle.
  • Social Networks: Reconstruction of latent sequences in temporally rewiring political and academic social networks from longitudinal data.

Methodology:

Temporally smoothed ℓ1-regularized logistic regression (lasso-style sparse structure recovery) formulated as a standard convex optimization problem and solved with generic convex solvers, with temporal smoothing across time points constrained by data sampling frequency.

Topics

Details

Tool Type:
library
Operating Systems:
Linux, Windows, Mac
Programming Languages:
MATLAB
Added:
8/3/2017
Last Updated:
11/24/2024

Operations

Data Inputs & Outputs

Statistical calculation

Publications

Ahmed A, Xing EP. Recovering time-varying networks of dependencies in social and biological studies. Proceedings of the National Academy of Sciences. 2009;106(29):11878-11883. doi:10.1073/pnas.0901910106. PMID:19570995. PMCID:PMC2704856.

Documentation

Links