ThermoBase
ThermoBase provides a curated database of thermophilic and hyperthermophilic organisms (those that thrive above 40°C), compiling taxonomic, metabolic, environmental, experimental, and physiological parameters to support comparative analyses and experimental design.
Key Features:
- Extensive Organism Descriptions: Contains curated entries for 1238 thermophilic and hyperthermophilic organisms with taxonomic, metabolic, environmental, experimental, and physiological data.
- Standardized Data Parameters: Reports standardized organism limits and tolerances including coupling ions for chemiosmosis, optimal pH and pH range, temperature and temperature range, pressure, and salinity.
- Consolidated Literature References: Centralizes literature resources and primary-source data relevant to thermophiles and hyperthermophiles to facilitate data retrieval and comparison.
Scientific Applications:
- Biotechnological Research: Supports identification of thermophile traits and growth conditions relevant to industrial processes operating at elevated temperatures.
- Hypothesis Generation and Experimental Design: Enables generation and testing of hypotheses about adaptive mechanisms and evolutionary pathways by providing standardized physiological and environmental parameters.
- Literature Synthesis and Review: Provides organized access to relevant studies and data for systematic reviews and comparative analyses.
Methodology:
No computational methods or data-processing steps are specified in the provided description.
Topics
Details
- Cost:
- Free of charge
- Tool Type:
- web application
- Operating Systems:
- Mac, Linux, Windows
- Added:
- 8/16/2022
- Last Updated:
- 8/16/2022
Operations
Publications
DiGiacomo J, McKay C, Davila A. ThermoBase: A database of the phylogeny and physiology of thermophilic and hyperthermophilic organisms. PLOS ONE. 2022;17(5):e0268253. doi:10.1371/journal.pone.0268253. PMID:35536846. PMCID:PMC9089862.