tiledb-vcf

Open source python package that uses serverless TileDB multidimensional arrays indexed on chromosome, position, and sample to enable variant warehousing scalable to thousands of samples. Offers lossless import VCF or gVCF files, the latter in an N+1 compliant manner. Can be combined with TileDB-Cloud powers real-time queries for variant browsers as well as large notebook-based analyses that use task graphs in conjunction with user-defined functions.