Timesias

Timesias predicts clinical outcomes from real-time sequential clinical data in hospital settings, with a primary focus on early detection of sepsis.


Key Features:

  • Real-Time Prediction: Processes sequential clinical data in real time to generate timely risk estimates.
  • Outcome Prediction: Targets early onset of sepsis among hospitalized patients.
  • Performance Metrics: Reported area under the receiver operator characteristic curve (AUROC) of 0.85 in challenge evaluation.
  • Benchmark Evaluation: Ranked first place in the DII (Discover, Innovate, Impact) National Data Science Challenge using a dataset of over 100,000 patient records.
  • Scalability: Pipeline designed to handle large clinical datasets.
  • Machine Learning Pipeline: Implements machine learning algorithms to extract predictive patterns from time-series clinical records.

Scientific Applications:

  • Early Detection: Predicts sepsis onset to support earlier clinical intervention and patient monitoring.
  • Clinical Decision Support: Provides time-series-derived risk estimates to inform clinical decision-making and surveillance in hospital settings.

Methodology:

Leverages machine learning algorithms to process and analyze sequential clinical records and extract patterns predictive of sepsis, with a pipeline designed to handle large datasets.

Topics

Details

License:
MIT
Cost:
Free of charge
Tool Type:
library
Operating Systems:
Mac, Linux, Windows
Programming Languages:
Python
Added:
11/17/2021
Last Updated:
11/17/2021

Operations

Publications

Zhang H, Yi D, Guan Y. Timesias: A machine learning pipeline for predicting outcomes from time-series clinical records. STAR Protocols. 2021;2(3):100639. doi:10.1016/j.xpro.2021.100639. PMID:34258599. PMCID:PMC8260877.

PMID: 34258599
PMCID: PMC8260877
Funding: - National Science Foundation: 1452656 - National Institutes of Health: R35-GM133346

Links