TimeTree

TimeTree aggregates divergence-time estimates from molecular evolution and phylogenetics literature to provide comparative timetrees and timelines for studying species divergence and evolutionary timescales.


Key Features:

  • Data aggregation: Aggregates peer-reviewed publications in molecular evolution and phylogenetics to derive divergence-time estimates.
  • Extensive database: Contains data from over 3,000 studies and more than 97,000 species spanning the tree of life.
  • Timetree and timeline generation: Produces timetrees for groups of species and timelines that trace the evolutionary history of individual species over time.
  • Integration with geological and environmental history: Aligns divergence-time information with Earth's geological events and environmental history.
  • Statistical synthesis: Synthesizes molecular clock analyses to produce summary statistics of divergence times from hierarchical data.

Scientific Applications:

  • Biodiversity studies: Provides temporal context for speciation and diversification analyses across taxa.
  • Evolutionary development (evo-devo): Supplies divergence-time estimates for comparative analyses of developmental processes.
  • Disease research: Offers evolutionary timescales relevant to comparative studies of disease-related lineages.

Methodology:

Aggregates divergence-time estimates from peer-reviewed molecular evolution and phylogenetics literature, interprets complex and hierarchical molecular-clock analyses, and synthesizes these data into summary statistics and visual representations.

Topics

Details

Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Added:
8/3/2017
Last Updated:
6/21/2022

Operations

Publications

Kumar S, Stecher G, Suleski M, Hedges SB. TimeTree: A Resource for Timelines, Timetrees, and Divergence Times. Molecular Biology and Evolution. 2017;34(7):1812-1819. doi:10.1093/molbev/msx116. PMID:28387841.

Kumar S and Hedges SB. TimeTree2: species divergence times on the iPhone. Bioinformatics. 2011; 27:2023-4. doi: 10.1093/bioinformatics/btr315

PMID: 21622662

Documentation

Links