TogoTable

TogoTable annotates user-uploaded biological tables by querying Resource Description Framework (RDF) databases and integrating annotations from the Linked Open Data (LOD) network via SPARQL.

Key Features:

• User-Specified Annotations: Supports specifying which annotations or properties to add to uploaded tables.
• Integration with RDF-Based Databases: Queries and integrates data from multiple RDF-compliant databases using the W3C Resource Description Framework model.
• SPARQL Query Language Support: Executes SPARQL queries against SPARQL endpoints for precise retrieval from RDF stores.
• Cross-Database Linking: Links annotations across databases, for example retrieving Protein Data Bank annotations using GeneID via UniProt RDF.

Scientific Applications:

• High-throughput data annotation: Automates annotation of large experimental datasets, such as those from high-throughput experiments, by integrating diverse RDF-linked biological data sources.

Methodology:

Uses database identifiers in uploaded tables as query keys to search RDF-based databases through SPARQL endpoints and integrates retrieved annotations into the original dataset.