TomoMQA

TomoMQA automates quality assurance of mega-voltage computed tomography (MVCT) images from helical tomotherapy platforms to assess imaging performance and consistency for radiation therapy treatment planning.

Key Features:

• DICOM importation: Opens DICOM dataset folders produced by helical tomotherapy systems for analysis.
• Helical tomotherapy compatibility: Supports MVCT data from TomoTherapy® and Radixact™ platforms, including TomoTherapy® HD and HDA models.
• Baseline consistency testing: Compares MVCT scans to pre-existing baseline data or generates a new baseline during analysis.
• TG-148 compliance: Implements QA procedures and default tolerance values recommended by TG-148 for MVCT QA.
• Adjustable tolerances: Allows manual modification of TG-148 default tolerance values used in the analysis.
• Report generation: Produces comprehensive QA reports summarizing analysis results and comparisons to baseline values.
• Implementation: Developed and executed in MATLAB.

Scientific Applications:

• Routine MVCT QA: Assess and document imaging performance of MVCT acquisitions on helical tomotherapy systems.
• Longitudinal consistency monitoring: Detect temporal changes in MVCT image quality through baseline comparisons.
• Standards compliance verification: Verify MVCT datasets against TG-148 recommended tolerance values.
• Cross-machine evaluation: Applied to a study of 15 MVCTs from five helical tomotherapy machines (one TomoTherapy® HD, two TomoTherapy® HDA, and two Radixact™) collected over three months.

Methodology:

Implemented in MATLAB; opens DICOM dataset folders from helical tomotherapy systems, performs baseline consistency testing by comparing to or generating baseline data, applies TG-148 recommended tolerance values (modifiable), and generates a comprehensive QA report.