TORTE

TORTE enables real-time extraction of oscillatory phase and amplitude to support closed-loop neural perturbation experiments focused on neural oscillations.

Key Features:

• Oscillatory phase and amplitude extraction: Extracts phase and amplitude from target neural signals for analysis and control.
• Real-time estimation: Produces real-time estimates of oscillatory characteristics for use in closed-loop experiments.
• Closed-loop perturbation triggering: Provides options to trigger perturbations based on real-time estimates of oscillatory phase and amplitude.
• Open Ephys GUI (OEGUI) integration: Interfaces with the Open Ephys GUI to receive acquisition data from a range of recording systems.
• Low-latency, high-accuracy processing: Implements fast, low-latency processing with accuracy comparable to existing analytic signal extraction methods used in closed-loop perturbations.

Scientific Applications:

• Causal testing of oscillation-behavior relationships: Enables experiments that manipulate neural oscillations to test causal links between brain activity and behavior.
• Mechanistic studies of cognitive functions: Supports investigations into how oscillatory dynamics influence cognitive processes.
• Neurophysiological investigations of disorders: Facilitates studies probing oscillatory alterations in neurological disorders and their potential therapeutic modulation.

Methodology:

Real-time extraction of oscillatory phase and amplitude from target signals; generation of real-time oscillatory characteristic estimates; triggering of closed-loop perturbations based on those estimates; interfacing with Open Ephys GUI for acquisition data.