transomics2cytoscape

transomics2cytoscape enables automated visualization of 2.5-dimensional trans-omic networks, facilitating mechanistic interpretation of omics data.

Key Features:

• Automated 2.5D Visualization: Generates isometric views of stacked X-Y planes representing multiple omics layers without manual drawing.
• Rapid Network Redrawing: Supports frequent update and redrawing of trans-omics networks to align with progress in multi-omics/trans-omics data analysis.
• Network-based Interpretation: Enables interpretation of multi-omics data at each research step through automated network generation.

Scientific Applications:

• Multi-omics Data Integration: Visualizes multi-omics/trans-omics data in the context of conventional biochemical network layouts drawn on stacked omics layers.
• Mechanistic Interpretation of Omics Data: Facilitates network-based interpretation of omics data for understanding biological mechanisms.
• Reproduction of Published Networks: Rapidly reproduces trans-omics networks presented in published papers within minutes.

Methodology:

transomics2cytoscape is implemented as an R Bioconductor package that automates the creation of 2.5D visualizations of trans-omic networks.