TraVis Pies

TraVis Pies visualizes tracer metabolomics data by integrating metabolite abundances, tracer incorporation patterns, and positions on metabolic maps to support interpretation of metabolic pathway alterations.


Key Features:

  • Integrated visualization: Visualizes and overlays metabolite abundances, tracer incorporation, and positions on metabolic maps to represent labeling patterns and distribution.
  • Structured interpretation framework: Provides a structured methodology for analyzing tracer metabolomics data to interpret labeling patterns within metabolic pathways.

Scientific Applications:

  • Disease-related pathway analysis: Facilitates interpretation of tracer metabolomics datasets to elucidate metabolic pathways altered in disease and to investigate tracer-derived labeling patterns linked to metabolic mechanisms.
  • Identification of metabolic signatures: Supports identification of metabolic alterations that may inform potential therapeutic targets or diagnostic markers based on tracer labeling.

Methodology:

Integrates metabolite abundances, tracer incorporation, and metabolic map positions into coherent visual representations of labeling patterns.

Topics

Collections

Details

License:
Apache-2.0
Cost:
Free of charge
Tool Type:
web application
Operating Systems:
Linux
Programming Languages:
R
Added:
11/23/2022
Last Updated:
11/24/2024

Operations

Publications

De Craemer S, Driesen K, Ghesquière B. TraVis Pies: A Guide for Stable Isotope Metabolomics Interpretation Using an Intuitive Visualization. Metabolites. 2022;12(7):593. doi:10.3390/metabo12070593. PMID:35888717. PMCID:PMC9321460.

PMID: 35888717
PMCID: PMC9321460
Funding: - KU Leuven C1: C14/17/110

Documentation

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