TRTools

TRTools provides harmonization and analysis utilities for genome-wide tandem repeat (TR) genotyping by standardizing genotype file formats and enabling filtering, merging, and quality control of TR genotype data.

Key Features:

• Integration with Genotyping Tools: Compatibility with outputs from a wide range of tandem repeat genotyping tools via an internal harmonization module that standardizes genotype file formats.
• Comprehensive Utility Suite: Utilities for filtering, merging, and performing quality control on TR genotype data.

Scientific Applications:

• Genetic variation analysis: Enables analysis of tandem repeat variation by integrating and standardizing TR genotype data for downstream studies.
• Evolutionary biology: Supports studies of TR variation relevant to evolutionary and population-genetic questions.
• Disease association research: Facilitates disease association studies by producing processed and quality-controlled TR genotype datasets for downstream analyses.

Methodology:

Harmonizing genotype files from various tandem repeat genotyping tools by standardizing genotype file formats and providing utilities for filtering, merging, and quality control of TR genotype data.