UNaProd

UNaProd provides a curated database of natural medicinal substances from Iranian Traditional Medicine (ITM) to standardize ITM concepts and support systems biology and systems pharmacology research.

Key Features:

• Extensive monograph collection: Contains 2,696 monographs covering herbal, animal, and mineral medicinal substances derived primarily from "Makhzan al-Advieh".
• Attribute-rich entries: Each entry includes 16 distinct attributes, such as origin and scientific name, to support structured analysis.
• Standardization of ITM concepts: Reorganizes and standardizes ITM materia medica terminology and concepts for computational use.
• Integration with systems biology: Supports systems medicine and systems pharmacology approaches to rationalize traditional medicine uses and infer potential therapeutic relationships.
• Cross-database links: Interconnected with IrGO and CMAUP to provide additional information on Mizaj (temperament) and molecular features.

Scientific Applications:

• Systems pharmacology modeling: Provides structured input for building models linking traditional drugs to biological targets and diseases.
• Mechanism and efficacy exploration: Facilitates investigation of potential mechanisms of action and efficacy of ITM natural products.

Methodology:

Data were extracted from "Makhzan al-Advieh" using text mining methods and manual editing to produce a structured database.