Utopia

Utopia organizes and integrates biological data to support protein sequence viewing and alignment, three-dimensional molecular structure rendering, and real-time interaction with large-scale datasets for bioinformatics analysis.


Key Features:

  • Ontology-Driven Data Model: Leverages an ontology-driven framework to organize and interpret complex biological data.
  • Protein Sequence Viewing and Alignment: Provides capabilities for viewing and aligning protein sequences.
  • Three-Dimensional Molecular Structure Rendering: Renders intricate molecular structures in three dimensions.
  • Integration of Diverse Resources: Accesses web services and various data objects for data integration.
  • Real-Time Interaction with Large Datasets: Supports real-time interaction and operations on large-scale biological databases.
  • High-Performance Rendering and Distributed Systems: Incorporates high-performance rendering techniques and distributed systems expertise to enhance visualization and processing speed.
  • Architectural Soundness Guided by HCI Expertise: Built with an architectural foundation informed by human–computer interaction expertise.

Scientific Applications:

  • Large-Scale Data Analysis: Enables analysis workflows on large biological datasets through real-time interaction and data integration.
  • Structure-Sequence Integration: Supports combined analysis of protein sequences and three-dimensional molecular structures.
  • Integrated Visualization and Data Manipulation: Integrates data manipulation tools with visualization systems to facilitate complex bioinformatics analyses.
  • Automated and Expert-Guided Analyses: Accommodates both automated processing and analyses requiring domain expert interpretation.

Methodology:

Implements an ontology-driven framework with protein sequence alignment and viewing, three-dimensional molecular rendering, integration with web services and data objects, real-time interaction with large datasets, high-performance rendering techniques, distributed systems, and reusable software components.

Topics

Details

Tool Type:
desktop application
Operating Systems:
Windows, Mac
Added:
12/18/2017
Last Updated:
11/25/2024

Operations

Publications

Pettifer SR, Sinnott JR, Attwood TK. UTOPIA—user‐friendly tools for operating informatics applications. Comparative and Functional Genomics. 2004;5(1):56-60. doi:10.1002/cfg.359. PMID:18629035. PMCID:PMC2447318.

Pettifer S, Wolstencroft K, Alper P, Attwood T, Coletta A, Goble C, Li P, McDermott P, Marsh J, Oinn T, Sinnott J, Thorne D. $^{\textrm{\small{my}}}$ Grid and UTOPIA: An Integrated Approach to Enacting and Visualising in Silico Experiments in the Life Sciences. Lecture Notes in Computer Science. None. doi:10.1007/978-3-540-73255-6_8.

Links