VANTED

VANTED enables visualization, integration, analysis, and simulation of networks containing biomolecular entities over time using multi-omics experimental datasets to support systems biology investigations.

Key Features:

• Network Reconstruction: Reconstructs biological networks from diverse omics datasets to represent interactions among biomolecular entities.
• Data Visualization: Provides advanced visualization of large-scale data within the context of functional pathways and hierarchies.
• Integration of Various Data Types: Integrates multiple types of omics data into a unified framework for combined analysis.
• Network Simulation: Simulates network dynamics to predict system behavior under different conditions.
• Data Exploration: Enables multi-perspective exploration of datasets by combining several analytical tasks.
• Standards Support: Adheres to systems biology standards for visualization and data exchange to ensure interoperability.
• Statistical Analysis: Provides statistical tools for analyzing omics data and supporting hypothesis testing.

Scientific Applications:

• Pathway Analysis: Maps and analyzes biological pathways to uncover insights into cellular processes.
• Functional Hierarchies Exploration: Examines hierarchical relationships within biological systems to identify key regulatory elements.
• Omics Data Analysis and Hypothesis Testing: Performs statistical analysis of multi-omics data to validate findings and support hypothesis generation.

Methodology:

Performs network reconstruction, integrates multiple omics datasets, visualizes data in pathway and hierarchy contexts, simulates network dynamics, and supports statistical analysis and exploratory data analysis.