Vapur

Vapur indexes protein–chemical pairs in CORD-19 abstracts to enable retrieval of studies linking proteins and chemicals relevant to COVID-19.


Key Features:

  • Relation-Oriented Inverted Index: Constructs a semantic inverted index that groups and retrieves publications based on extracted relations between proteins and chemicals rather than keyword matches.
  • BioNLP Pipeline Integration: Employs a BioNLP pipeline to perform named entity recognition and relation extraction on CORD-19 abstracts to populate the relation-oriented index.

Scientific Applications:

  • Protein–chemical relationship discovery: Identifies literature reporting associations between specific proteins and chemicals within the COVID-19 corpus.
  • Therapeutic target identification: Surfaces publications that link proteins and chemicals to support identification of candidate targets for COVID-19 research.
  • Molecular interaction literature mining: Aggregates evidence of molecular interactions from CORD-19 abstracts for downstream bioinformatics analysis.

Methodology:

Named entity recognition and relation extraction are applied to CORD-19 abstracts via a BioNLP pipeline to build a semantic, relation-oriented inverted index.

Topics

Details

Programming Languages:
Python
Added:
1/18/2021
Last Updated:
3/11/2021

Operations

Publications

Köksal A, Dönmez H, Özçelik R, Ozkirimli E, Özgür A. Vapur: A Search Engine to Find Related Protein - Compound Pairs in COVID-19 Literature. Unknown Journal. 2020. doi:10.1101/2020.09.05.284224.

Links