Vapur
Vapur indexes protein–chemical pairs in CORD-19 abstracts to enable retrieval of studies linking proteins and chemicals relevant to COVID-19.
Key Features:
- Relation-Oriented Inverted Index: Constructs a semantic inverted index that groups and retrieves publications based on extracted relations between proteins and chemicals rather than keyword matches.
- BioNLP Pipeline Integration: Employs a BioNLP pipeline to perform named entity recognition and relation extraction on CORD-19 abstracts to populate the relation-oriented index.
Scientific Applications:
- Protein–chemical relationship discovery: Identifies literature reporting associations between specific proteins and chemicals within the COVID-19 corpus.
- Therapeutic target identification: Surfaces publications that link proteins and chemicals to support identification of candidate targets for COVID-19 research.
- Molecular interaction literature mining: Aggregates evidence of molecular interactions from CORD-19 abstracts for downstream bioinformatics analysis.
Methodology:
Named entity recognition and relation extraction are applied to CORD-19 abstracts via a BioNLP pipeline to build a semantic, relation-oriented inverted index.
Topics
Details
- Programming Languages:
- Python
- Added:
- 1/18/2021
- Last Updated:
- 3/11/2021
Operations
Publications
Köksal A, Dönmez H, Özçelik R, Ozkirimli E, Özgür A. Vapur: A Search Engine to Find Related Protein - Compound Pairs in COVID-19 Literature. Unknown Journal. 2020. doi:10.1101/2020.09.05.284224.
Links
Repository
https://github.com/boun-tabi/vapur