vcfppR

vcfppR provides R bindings for the vcfpp C++ API, enabling rapid processing of Variant Call Format (VCF/BCF) files for efficient variant analysis.

Key Features:

• High-performance VCF/BCF manipulation: Leverages the vcfpp C++ API built on HTSlib for rapid and safe file operations.
• Single-file C++ API integration: Wraps the portable, single-file vcfpp C++ library for use in R.
• Intuitive interface: Provides straightforward access to variant data structures and operations within the R environment.

Scientific Applications:

• Large-scale variant analysis: Enables rapid processing of VCF/BCF files to support analyses of high-volume genomic variation data.
• Cross-language bioinformatics pipelines: Facilitates integration of C++-optimized VCF processing into R-based genomic workflows.

Methodology:

vcfppR is developed as an R package binding to the vcfpp C++ API, which is implemented as a single-file wrapper around HTSlib functions.