Vesicle Viewer

Vesicle Viewer analyzes small-angle scattering (SAS) data from unilamellar lipid bilayer vesicles to extract bilayer structural parameters such as area per lipid and bilayer thickness.

Key Features:

• Small-Angle Scattering (SAS) analysis: Performs analysis of SAS data from unilamellar lipid bilayer vesicles.
• Modified Scattering Density Profile (EZ-SDP): Implements the EZ-SDP approach to determine bilayer structural parameters including area per lipid and bilayer thickness.
• Asymmetric bilayer modeling: Models chemically and isotopically asymmetric lipid bilayers.
• SAXS and SANS support: Applies to small-angle X-ray scattering (SAXS) and small-angle neutron scattering (SANS) datasets.
• Computational stack: Uses Django with NumPy for computation and Matplotlib for plotting of scattering profiles and fits.

Scientific Applications:

• Membrane structure determination: Derives quantitative bilayer parameters from SAS experiments for structural biology studies.
• Asymmetric membrane analysis: Enables investigation of chemical and isotopic asymmetries in lipid bilayers.
• SAXS/SANS data interpretation: Supports analysis and fitting of SAXS and SANS datasets from unilamellar vesicles.

Methodology:

Implements modified Scattering Density Profile (EZ-SDP) analysis with computational components implemented using Django, NumPy and Matplotlib.