ViewBS
ViewBS visualizes and analyzes high-throughput bisulfite sequencing (BS-seq) data to generate and explore single-base DNA methylomes in plant and animal systems.
Key Features:
- Tabix integration: Integrates with Tabix to enable indexed access to large BS-seq datasets.
- Large dataset visualization: Provides rapid retrieval and visualization of extensive BS-seq data for large-scale methylome analyses.
- Publication-quality figures: Produces publication-quality visualizations, including meta-plots, heat maps, and violin-boxplots.
- Figure-generation toolkit: Includes a suite of tools to generate figures for exploring and interpreting methylome patterns.
Scientific Applications:
- Single-base methylome generation: Generation and exploration of single-base DNA methylomes from BS-seq data in plant and animal systems.
- Plant epigenomics: Visualization and interpretation of methylation patterns in Arabidopsis thaliana BS-seq datasets.
- Epigenetic analysis: Investigation of DNA methylation patterns and their implications for epigenetic modifications in biological contexts.
Methodology:
Uses Tabix-indexed BS-seq files for rapid data access and provides functions to generate meta-plots, heat maps, and violin-boxplots.
Topics
Details
- License:
- GPL-3.0
- Tool Type:
- command-line tool
- Operating Systems:
- Linux
- Programming Languages:
- Perl
- Added:
- 6/21/2018
- Last Updated:
- 11/25/2024
Operations
Publications
Huang X, Zhang S, Li K, Thimmapuram J, Xie S. ViewBS: a powerful toolkit for visualization of high-throughput bisulfite sequencing data. Bioinformatics. 2017;34(4):708-709. doi:10.1093/bioinformatics/btx633. PMID:29087450. PMCID:PMC5860610.
PMID: 29087450
PMCID: PMC5860610
Funding: - Natural Science Foundation of Jiangsu Province: BK20150681
- National Natural Science Foundation of China: 71704081