VirusDIP

VirusDIP integrates viral sequence data and analysis tools to support viral genomics, phylogenetics, and secure global data sharing.


Key Features:

  • Data Archive and Integration: Consolidates viral sequence submissions and integrates resources from the National GeneBank Database (CNGBdb), the Global Initiative on Sharing All Influenza Data (GISAID), and the National Center for Biotechnology Information (NCBI).
  • Data Access and Analysis: Provides BLAST sequence alignment, multi-sequence alignment, and phylogenetic tree building for evolutionary and comparative analyses.
  • Security and Collaboration: Employs multi-party security computing tools to enable secure and trusted data sharing among research groups.

Scientific Applications:

  • Epidemiological Studies: Enables tracking of viral spread and mutation patterns through integrated sequence datasets.
  • Evolutionary Research: Supports phylogenetic analyses to investigate virus evolution and lineage relationships.
  • Public Health Response: Facilitates rapid sharing and analysis of viral sequence data to inform outbreak investigation and response.

Methodology:

Integrates sequence data from CNGBdb, GISAID, and NCBI; performs BLAST-based sequence alignments and multi-sequence alignment and constructs phylogenetic trees; and applies multi-party security computing for secure data sharing.

Topics

Details

Added:
1/18/2021
Last Updated:
3/13/2021

Operations

Publications

Wang L, Chen F, Guo X, You L, Yang X, Yang F, Yang T, Gao F, Hua C, Ding Y, Cai J, Yang L, Huang W, Xu Z, Wan B, Tong J, Peng C, Yang Y, Zhang L, Liu K, Zhou F, Zhang M, Tan C, Zeng W, Wang B, Wei X. VirusDIP: Virus Data Integration Platform. Unknown Journal. 2020. doi:10.1101/2020.06.08.139451.