VISPR-online

VISPR-online provides visualization and exploration of CRISPR screening results to analyze gene essentiality, guide RNA (gRNA) read count changes, and gRNA locations.

Key Features:

• Multi-tool compatibility: Accepts and integrates outputs from MAGeCK, BAGEL, and JACKS for downstream analysis.
• Interactive visualization: Visualizes gene essentiality, read count changes, and guide RNA (gRNA) locations to support interpretation of CRISPR screens.
• Analysis sharing and resumption: Enables sharing and resumption of screening analyses and results among collaborators.

Scientific Applications:

• Gene essentiality analysis: Supports identification and visualization of essential genes from CRISPR screening data.
• Functional genomics and CRISPR screen interpretation: Facilitates interpretation of screening experiments across different analysis pipelines for functional genomics studies.

Methodology:

Integrates outputs from MAGeCK, BAGEL, and JACKS into a unified platform that supports interactive visualization and exploration of screening data.