VisSR

VisSR visualizes small RNAs (sRNAs), including microRNAs (miRNAs), alongside user-provided genomic features to support analysis of RNA silencing from next-generation sequencing (NGS) data.

Key Features:

• Scalability: Efficient processing of large sRNA datasets generated by next-generation sequencing (NGS).
• Visualization of sRNAs and genomic features: Generates visual representations of sRNAs, including miRNAs, aligned with genomic annotations.
• Integration with genomic features: Supports importing and co-visualizing user-supplied genomic features and annotations alongside sRNA data.

Scientific Applications:

• RNA silencing research: Analysis and visualization of sRNAs and miRNAs to investigate RNA silencing mechanisms.
• Developmental biology: Studying the roles of sRNAs and miRNAs in development.
• Pathogen interaction studies: Examining sRNA-mediated pathogen control mechanisms.
• Genome maintenance studies: Investigating sRNAs involved in genome maintenance.
• Environmental response studies: Analyzing sRNA expression and roles in responses to environmental changes.

Methodology:

Part of the UEA sRNA workbench suite; implements efficient data processing and visualization of sRNA (including miRNA) datasets derived from next-generation sequencing (NGS).