VOLTA

VOLTA performs co-expression network analysis of transcriptomics data to construct, compare, and identify communities and functional modules within gene co-expression networks.

Key Features:

• Customizable Network Analysis: Supports construction and manipulation of various network types and exposes individual functions to assemble bespoke workflows or use predefined pipelines.
• Multiple Algorithm Options: Implements multiple algorithms for each analysis step, including community detection and clustering algorithms.
• Predefined Analysis Pipelines: Provides end-to-end predefined pipelines for co-expression network workflows.
• Transcriptomics Focus: Specialized for networks derived from transcriptomics experiments and gene expression data.

Scientific Applications:

• Gene co-expression analysis: Construction and analysis of gene co-expression networks from transcriptomic datasets.
• Community and module detection: Identification and characterization of network communities and functional modules.
• Regulatory and interaction inference: Exploration of genetic interactions and regulatory mechanisms through network structure and modules.

Methodology:

Integrates multiple algorithms (including community detection and clustering), exposes individual functions, and provides customizable and predefined pipelines for co-expression network construction and analysis.