WeBCMD

WeBCMD models and analyzes brain dynamics by integrating multimodal physiological data to support mathematical model development and interpretation of healthy and injured cerebral dynamics.

Key Features:

• BCMD framework integration: Developed as part of the BCMD (Brain Computational Modelling Development) framework.
• Brain dynamics modeling: Performs computational modeling and analysis of cerebral dynamics.
• Multimodal data integration: Integrates near-infrared spectroscopy (NIRS) measurements, including haemoglobin oxygenation and the redox state of cytochrome-c-oxidase, with systemic signals.
• Systemic signal analysis: Incorporates systemic physiological signals such as blood pressure to assess their effects on cerebral measurements.
• Mathematical model support: Supports development and testing of mathematical models to elucidate processes underlying brain activity.

Scientific Applications:

• Mathematical model development: Developing and testing mathematical models that elucidate mechanisms contributing to brain activity.
• Multimodal physiological analysis: Analyzing multimodal datasets (NIRS and systemic signals) to study cerebral physiology in health and injury.
• Physiological interaction assessment: Investigating interactions between cerebral measures and systemic variables such as blood pressure.

Methodology:

Uses advanced computational frameworks to integrate physiological measurements (NIRS haemoglobin oxygenation, cytochrome-c-oxidase redox state, and systemic signals such as blood pressure) for constructing and analyzing models of brain dynamics.