WebGeSTer DB

WebGeSTer DB catalogs intrinsic transcription terminators identified in bacterial genomes and plasmids to support analysis of prokaryotic transcription termination and gene regulation.

Key Features:

• Extensive data collection: Contains over one million intrinsic transcription terminators derived from 1,060 bacterial genomes and 798 plasmid sequences.
• Terminator classification: Includes both canonical and non-canonical intrinsic transcription terminators.
• Identification and cataloging: Terminators have been identified and cataloged across genome sequences to create a comprehensive repository.
• Genome-scale and targeted analyses: Includes results from whole-genome analyses and targeted investigations of terminators located downstream of specific genes.
• Distribution data: Provides information on terminator prevalence and distribution across different bacterial phyla.

Scientific Applications:

• Gene regulation analysis: Enables study of intrinsic termination mechanisms underlying bacterial gene expression.
• Comparative genomics: Supports comparative analysis of terminator prevalence and types across bacterial phyla.
• Functional inference: Facilitates investigation of the roles of canonical and non-canonical terminators in prokaryotic transcription termination.

Methodology:

Identification and cataloging of intrinsic transcription terminators from extensive genomic data sets, including whole-genome analyses and targeted investigations of terminators downstream of specific genes.