webSalvador

webSalvador analyzes Luria-Delbrück fluctuation experiment data to estimate mutation rates and perform statistical and visualization analyses of spontaneous mutations.


Key Features:

  • rSalvador integration: Encapsulates most functions available in the R package rSalvador for fluctuation analysis.
  • Mutation rate estimation: Provides quantitative estimation of mutation rates from fluctuation experiment data.
  • Statistical evaluation: Performs statistical evaluation of experimental data from Luria-Delbrück fluctuation experiments.
  • Visualization: Generates visualizations to support interpretation of mutation distributions and results.
  • Containerized deployment: Packaged as a Docker image for consistent computational deployment.

Scientific Applications:

  • Fluctuation experiment analysis: Analysis and interpretation of Luria-Delbrück fluctuation experiment datasets to study spontaneous mutations.
  • Mutation rate quantification: Quantitative estimation of mutation rates using fluctuation experiment data.
  • Statistical and visual interpretation: Statistical testing and visualization of fluctuation experiment results to support biological interpretation of mutation processes.

Methodology:

Implements functions from the R package rSalvador and is distributed as a Docker image.

Topics

Details

Tool Type:
web application
Programming Languages:
R
Added:
1/2/2022
Last Updated:
1/2/2022

Operations

Publications

Zheng Q. webSalvador: a Web Tool for the Luria-Delbrük Experiment. Microbiology Resource Announcements. 2021;10(20). doi:10.1128/mra.00314-21. PMID:34016679. PMCID:PMC8141511.

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