WHOOPER

WHOOPER facilitates the analysis of protein co-occurrence across taxa by integrating HHblits and HMMER to identify remote homologs across extensive proteomic datasets.


Key Features:

  • Remote Homolog Detection: Integrates HHblits and HMMER for efficient detection of remote homologs across extensive proteomic datasets.
  • Data Representation and Filtering: Combines an original data representation with advanced dynamic filtering functionalities for real-time exploration of alignment data.
  • Export Capabilities: Supports seamless export for downstream evolutionary and functional genomics research.

Scientific Applications:

  • Protein Prevalence Analysis: Streamlines workflows for studying protein prevalence across taxa.
  • Protein Co-occurrence Analysis: Enables analysis of protein co-occurrence patterns among phyla.
  • Phylogenetic Pattern Investigation: Supports investigation of phylogenetic patterns in proteomic data.
  • Evolutionary Genomics: Facilitates downstream evolutionary genomics research through data export.
  • Functional Genomics: Facilitates downstream functional genomics research through data export.

Methodology:

WHOOPER integrates HHblits and HMMER for remote homolog detection across proteomic datasets.

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Details

Added:
2/22/2026
Last Updated:
2/22/2026

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