XePhIR

XePhIR aggregates standardized zebrafish xenograft phenotype data and associated metadata to support comparative analyses and reproducibility in cancer research.

Key Features:

• Data Standardization: Provides standardized protocols and metadata schemas to ensure consistency across zebrafish xenograft experiments.
• Interactive Repository: Enables deposition of detailed experimental data and metadata, including representative images capturing early cancer development post-engraftment in zebrafish embryos.
• Enhanced Reproducibility and Traceability: Associates deposited datasets with corresponding peer‑reviewed publications to improve reproducibility and traceability of zebrafish xenograft studies.

Scientific Applications:

• Model Validation: Allows validation of zebrafish xenograft experimental models against repository datasets.
• Comparative Studies: Facilitates comparative analyses across different zebrafish xenograft models using standardized protocols and extensive metadata.
• Reproducibility and Transparency: Supports reproducibility and methodological transparency by providing access to curated datasets and standardized protocols.

Methodology:

Systematic collection and curation of datasets from published zebrafish xenograft studies, with dataset deposition occurring after acceptance of the corresponding publication.