yeastgenome
yeastgenome provides gene annotation and high-resolution transcriptome visualization for Saccharomyces cerevisiae to support functional characterization of genes and transcript isoforms.
Key Features:
- Integration with SGD: Integrates manually curated gene annotations and experimental data from the Saccharomyces Genome Database (SGD).
- JBrowse visualization: Integrates with JBrowse to visualize transcript isoform data at high resolution.
- Transcript isoform incorporation: Incorporates published transcript isoform datasets for high-resolution profiling of RNA transcripts.
- Gene annotation: Provides curated annotations of the Saccharomyces cerevisiae reference genome and gene products.
- Untranslated region data: Includes transcript isoform and untranslated region (UTR) information for transcript boundary analysis.
- Expression quantification support: Links transcriptome data with annotations to support expression quantification analyses.
Scientific Applications:
- Gene functional characterization: Supports annotation-driven studies to elucidate gene functions and gene products in S. cerevisiae.
- Transcriptional regulation: Enables analysis of transcript isoforms and expression profiles to study transcriptional regulation in S. cerevisiae.
- Untranslated regions (UTRs): Facilitates analysis of UTR structures and isoforms using integrated transcript data.
- Genome engineering: Supports detailed studies of genomic loci and annotations relevant to genome engineering in S. cerevisiae.
- Expression quantification: Facilitates quantification of RNA expression by combining transcript isoform datasets with genomic annotations.
Methodology:
Incorporates published transcript isoform datasets into JBrowse and integrates manually curated experimental annotations from the Saccharomyces Genome Database (SGD) to enable high-resolution RNA transcript profiling.
Topics
Details
- Added:
- 1/9/2020
- Last Updated:
- 11/24/2024
Operations
Publications
Ng PC, Wong ED, MacPherson KA, Aleksander S, Argasinska J, Dunn B, Nash RS, Skrzypek MS, Gondwe F, Jha S, Karra K, Weng S, Miyasato S, Simison M, Engel SR, Cherry JM. Transcriptome visualization and data availability at the Saccharomyces Genome Database. Nucleic Acids Research. 2019;48(D1):D743-D748. doi:10.1093/nar/gkz892. PMID:31612944. PMCID:PMC7061941.