Zorn

Zorn enables reproducible analysis, exploration, and visualization of single-cell metagenomic data from microbial communities.

Key Features:

• Workflow Management: Zorn functions as an R package and workflow manager for single-cell metagenomic analysis.
• Scalability: Zorn is built upon the Bascet system to handle scalable single-cell metagenomic analysis.
• Data Exploration and Visualization: Zorn supports exploration and visualization of single-cell microbial communities.
• Reproducibility: Zorn enables reproducible single-cell metagenomic data analysis.

Scientific Applications:

• Mock Community Analysis: Zorn was used to develop and optimize a high-throughput single-cell metagenomic method on a ten-species mock community.
• Clinical Sample Analysis: Zorn was applied to human saliva to generate single-amplified genomes from greater than 15,000 prokaryotic cells, including uncultured, low-abundance taxa undetected by bulk metagenomics.

Methodology:

Zorn is built upon the Bascet system and operates as an R package and workflow manager.