Quiz: UniProt

1. What is the primary purpose of UniProt?

2. Which organizations are part of the UniProt Consortium?

3. What is the purpose of UniParc (UniProt Archive)?

4. What distinguishes UniProtKB/Swiss-Prot from UniProtKB/TrEMBL?

Swiss-Prot focuses on unreviewed sequences, while TrEMBL is manually curated.
Swiss-Prot is a comprehensive resource, while TrEMBL is limited to certain protein types.
Swiss-Prot is a treasure trove of protein sequences, while TrEMBL is the gold standard.
Swiss-Prot is manually curated and considered a gold standard, while TrEMBL contains computationally analyzed sequences.
None of the above
All of the above

5. Why is UniProtKB/Swiss-Prot considered the gold standard?

6. What is the key characteristic of UniRef100??

It includes sequences with 50% identity.
It contains identical sequences and fragments with at least 11 amino acid residues.
It focuses on sequences with 90% identity.
It excludes sequences from fully sequenced genomes.
None of the above
All of the above

7. How does UniRef reduce the search space for researchers?

8. What is the primary advantage of the flatfile format used by Swiss-Prot and TrEMBL?

9. Which database uses the ASN.1 format for storing biological sequences?

10. What is a potential limitation of using UniProtKB/TrEMBL for critical research applications?

Protein Sequence Databases