2SigFinder

'2SigFinder' is a method for detecting genomic islands, regions in microbial genomes that bear distinctive genomic signatures. Unlike existing methods, it employs both small-scale and large-scale statistical testing to account for variations in genomic features across different scales.

Topic

Genomics;Statistics and probability;Functional, regulatory and non-coding RNA;Transcription factors and regulatory sites;Evolutionary biology

Detail

  • Operation: Virulence prediction;CpG island and isochore detection;Genome annotation

  • Software interface: Web user interface

  • Language: MATLAB,C

  • License: -

  • Cost: Free

  • Version name: -

  • Credit: National Natural Science Foundation of China.

  • Input: -

  • Output: -

  • Contact: Qi Dai daiailiu04@yahoo.com

  • Collection: -

  • Maturity: -

Publications

  • 2SigFinder: the combined use of small-scale and large-scale statistical testing for genomic island detection from a single genome.
  • Kong R, et al. 2SigFinder: the combined use of small-scale and large-scale statistical testing for genomic island detection from a single genome. 2SigFinder: the combined use of small-scale and large-scale statistical testing for genomic island detection from a single genome. 2020; 21:159. doi: 10.1186/s12859-020-3501-2
  • https://doi.org/10.1186/S12859-020-3501-2
  • PMID: 32349677
  • PMC: PMC7191778

Download and documentation

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