ADMIXMAP

ADMIXMAP is a software tool to estimate admixture and detects linkage in admixed populations. The ADMIXMAP algorithm uses Bayesian inference

Topic

Population genetics;Genotype and phenotype

Detail

  • Operation: Modelling and simulation

  • Software interface: Command-line user interface

  • Language: C++

  • License: -

  • Cost: Free

  • Version name: 3.7

  • Credit: National Institutes of Health (NIH).

  • Input: genotypesfile, testgenotypesfile,allelefreqfile, priorallelefreqfile, historicallelefreqfile, outcomevarfile, covariatesfile,coxoutcomevarfile

  • Output: paramfile, regparamfile, dispparamfile, indadmixturefile, allelefreqoutputfile, ergodicaveragefile, admixturescorefile, allelicassociationscorefile, ancestryassociationscorefile, affectedsonlyscorefile, args.txt

  • Contact: Paul M McKeigue paul.mckeigue at ucd.ie

  • Collection: -

  • Maturity: -

Publications

  • Estimation of admixture and detection of linkage in admixed populations by a Bayesian approach: application to African-American populations.
  • McKeigue PM, Carpenter JR, Parra EJ, Shriver MD (2000). Estimation of admixture and detection of linkage in admixed populations by a Bayesian approach: application to African-American populations. Ann Hum Genet 64(Pt 2): 171-86.
  • https://doi.org/10.1017/S0003480000008022
  • PMID: 11246470
  • PMC: -
  • Control of confounding of genetic associations in stratified populations.
  • Hoggart CJ, Parra EJ, Shriver MD, Bonilla C, Kittles RA, et al. (2003). Control of confounding of genetic associations in stratified populations. Am J Hum Genet 72(6): 1492-1504.
  • https://doi.org/10.1086/375613
  • PMID: 12817591
  • PMC: PMC1180309
  • Design and analysis of admixture mapping studies.
  • Hoggart CJ, Shriver MD, Kittles RA, Clayton DG, McKeigue PM. Design and analysis of admixture mapping studies. Am J Hum Genet. 2004 May;74(5):965-78. doi: 10.1086/420855. Epub 2004 Apr 14. PMID: 15088268; PMCID: PMC1181989.
  • https://doi.org/10.1086/420855
  • PMID: 15088268
  • PMC: PMC1181989

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