AKID

AKID (Automatic Kinase-specific Interactions Detection) is a software tool to identify kinase-specific phosphorylation events in Eukaryotes. The AKIS algorithm uses Deep Neural Network and identifies kinase domains, residues responsible for target specificity, and target peptides.

Topic

Protein sites, features and motifs;Sequence analysis;Protein modifications

Detail

  • Operation: Post-translation modification site prediction;Protein interaction network analysis;Sequence motif recognition

  • Software interface: Command-line user interface;Web service

  • Language: R, Python

  • License: Not stated

  • Cost: Free

  • Version name: v1

  • Credit: ELIXIR-IIB (elixir-italy.org), CINECA.

  • Input: FASTA, UNIPROT accessions

  • Output: -

  • Contact: luca.parca@uniroma2.it

  • Collection: -

  • Maturity: Stable

Publications

  • Kinome-wide identification of phosphorylation networks in eukaryotic proteomes.
  • Parca L, Ariano B, Cabibbo A, Paoletti M, Tamburrini A, Palmeri A, Ausiello G, Helmer-Citterich M. Kinome-wide identification of phosphorylation networks in eukaryotic proteomes. Bioinformatics. 2019 Feb 1;35(3):372-379.
  • https://doi.org/10.1093/bioinformatics/bty545
  • PMID: 30016513
  • PMC: PMC6361239

Download and documentation


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