APIN
APIN is a deep learning model to identify antimicrobial peptide (AMP) sequences. The model utilizes an embedding layer and a multi-scale convolutional network, which contains multiple convolutional layers with varying filter lengths. This architecture allows the model to capture and use latent features from the input sequences at different scales.
The authors also proposed a fusion model that incorporates additional information to further improve APIN's performance. The results demonstrate that both the base and fusion models outperform state-of-the-art models on two AMP datasets and the Antimicrobial Peptide Database (APD)3 benchmark dataset. Additionally, the fusion model surpasses the state-of-the-art model on an anti-inflammatory peptides (AIPs) dataset in terms of accuracy.
Topic
Small molecules;Proteomics;Machine learning
Detail
Operation: Peptide identification;Protein feature detection;Filtering
Software interface: Command-line user interface
Language: Python
License: Not stated
Cost: Free of charge
Version name: -
Credit: National Natural Science Foundation of China.
Input: -
Output: -
Contact: Han Zhang zhanghan@nankai.edu.cn
Collection: -
Maturity: -
Publications
- Antimicrobial peptide identification using multi-scale convolutional network.
- Su X, et al. Antimicrobial peptide identification using multi-scale convolutional network. Antimicrobial peptide identification using multi-scale convolutional network. 2019; 20:730. doi: 10.1186/s12859-019-3327-y
- https://doi.org/10.1186/S12859-019-3327-Y
- PMID: 31870282
- PMC: PMC6929291
Download and documentation
Documentation: https://github.com/zhanglabNKU/APIN/blob/master/README.md
Home page: https://github.com/zhanglabNKU/APIN
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