Ambit-SMIRKS

Ambit-SMIRKS is a part of project and an extension of AMBIT-SMARTS. Ambit-SMIRKS brings the ability to parse SMIRKS linear notations into internal reaction representations, apply stored reactions against reactants for actual transformation, search reactions, handling of stereo information, and post-processing of product, among others.

Topic

Cheminformatics;Metabolomics;Protein structure analysis;Enzymes

Detail

  • Operation: Pathway or network analysis

  • Software interface: Web user interface

  • Language: Java

  • License: Apache-2.0

  • Cost: Free

  • Version name: -

  • Credit: CEFIC-LRI EEM9.3-IC-EEM9.4: Linking LRI Ambit chemoinformatics system with the IUCLID Substance database to support read across of substance endpoint data and category formation.

  • Input: -

  • Output: -

  • Contact: -

  • Collection: AMBIT

  • Maturity: -

Publications

  • Ambit-SMIRKS: a software module for reaction representation, reaction search and structure transformation.
  • Kochev N, Avramova S, Jeliazkova N. Ambit-SMIRKS: a software module for reaction representation, reaction search and structure transformation. J Cheminform. 2018 Aug 20;10(1):42. doi: 10.1186/s13321-018-0295-6. PMID: 30128804; PMCID: PMC6102164.
  • https://doi.org/10.1186/s13321-018-0295-6
  • PMID: 30128804
  • PMC: PMC6102164

Download and documentation


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