BioPlat

SUMMARY: Development of effective tools such as oligo-microarrays and next-generation sequencing methods for monitoring gene expression on a large scale has resulted in the discovery of gene signatures with prognostic/predictive value in various malignant neoplastic diseases. However, with the exponential growth of gene expression databases, biologists are faced with the challenge of extracting useful information from these repositories. Here, we present a software package, BioPlat (Biomarkers Platform), which allows biologists to identify novel prognostic and predictive cancer biomarkers based on the data mining of gene expression signatures and gene expression profiling databases. BioPlat has been designed as an easy-to-use and flexible desktop software application, which provides a set of analytical tools related to data extraction, preprocessing, filtering, gene expression signature calculation, in silico validation, feature selection and annotation that leverage the integration and reuse of gene expression signatures in the context of follow-up data.
AVAILABILITY AND IMPLEMENTATION: BioPlat is a platform-independent software implemented in Java and supported on GNU/Linux and MS Windows, which is freely available for download at http://www.cancergenomics.net.

BioPlat: a software for human cancer biomarker discovery.

BioPlat (Biomarkers Platform) is a desktop software package that enables biologists to identify cancer biomarkers by data mining gene expression signatures and profiling databases. The software offers a range of analytical tools, including data extraction, preprocessing, filtering, signature calculation, validation, feature selection, and annotation. BioPlat is easy to use and flexible, and it is available for free download for GNU/Linux and MS Windows platforms.

BioPlat

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